NAD⁺ precursorNR
Nicotinamide riboside is a form of vitamin B3 and a precursor of NAD+, a molecule essential for producing cellular energy and repairing DNA.
Up to 300 mg of NR a day (maximum authorised in the EU).
What it is
NAD+ levels fall with age, and that fall is considered one of the hallmarks of ageing. It is one of the most popular longevity actives.
What it is used for
The quiz suggests it when your answers justify it. It usually appears with these goals:
What the evidence says
Early data in people or, mostly, from the laboratory. It only appears at the advanced level, and we say so.
It consistently raises blood NAD⁺ levels; clinical benefits (energy, metabolism, ageing) have not yet been shown in humans.
| Year | What was studied | What was found | Source |
|---|---|---|---|
| 2018 | It reliably raises NAD+ | Crossover RCT in healthy adults: well tolerated and it effectively raised NAD+. NR does what it promises at the biochemical level. | Martens et al.Nature Communications |
| 2019 | Effect in muscle: mechanism yes, function not so much | Crossover trial with 12 older men, using 1 g a day for 21 days (more than three times the maximum authorised in the EU): it increased muscle NAD+ and lowered some inflammatory cytokines in the blood, without changing mitochondrial function. | Elhassan et al.Cell Reports |
| 2023 | The critical review | Review of the 25 studies published in people: NR has shown few clinically relevant effects and the literature tends to exaggerate those it finds. The strongest signal is for inflammation. | Damgaard and TreebakScience Advances |
What to look for on the label
- NR with EU authorisation.
- NMN received a favourable EFSA opinion in May 2026 (300 mg a day), but its authorisation is still pending.
Precautions
- Do not exceed 300 mg a day.
Where to find it
Products whose label meets what this profile asks for: form, dose per serving and nothing that contradicts it. Three at most: quality of the active comes first and, among the best, we look for one option in each price range. We choose by composition, not by who pays. The shops are European or ship to Europe.
-
Life ExtensionShips from the Netherlands€€€High endLife Extension
NAD+ Cell Formula 300 mg
300 mg of NR chloride (Niagen®) per capsule
For the reference dose1 capsule (the authorised maximum)View at Life Extension (opens in a new tab)Meets the criteria.
-
iHerbShips from the US, VAT included€€€High endTru Niagen
Nicotinamide riboside 300 mg
300 mg of NR chloride (Niagen®) per capsule
For the reference dose1 capsule (the authorised maximum)View at iHerb (opens in a new tab)Meets the criteria.
-
HSNShips from Spain€BudgetEssential Series
NRC 300 mg (nicotinamide riboside)
300 mg of NR chloride per capsule
For the reference dose1 capsule (the authorised maximum)View at HSN (opens in a new tab)Meets the criteria.
We link to the shop; we do not sell anything. Today we earn no commission on any link. If we ever do, the link will say so and the selection will not change: the label decides. Labels checked on 2 November 2026; check the one on the pack before you buy. All these shops deliver to the EU; some of their pages open in Spanish. How we are funded.
Nearby in the library
Is it for you?
The quiz decides from your answers, not from a profile.
Profile reviewed on 3 November 2026. Sources: EFSA, Regulation (EU) 432/2012 and published studies. Image: Chemical apparatus. Engraving by J. Pass, 1801. Wellcome Collection, public domain.
General information based on published scientific evidence and EU law. Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle, and are not intended to diagnose, treat or prevent any disease.
Do not exceed the daily dose stated on each product. If you take medication, have a medical condition or have any doubts, ask your doctor or pharmacist.