Full review: all 36 actives, their studies and their EU status, up to date. What changed
ShelfBase · Nutritional base
Volume03 / 36
Reviewed3 Nov 2026

Vitamin B12

Vitamin B12 is produced by bacteria and builds up in foods of animal origin.

Strong
Chemical apparatus. Engraving by J. Pass, 1801. Wellcome Collection, public domain.
Reference dose250–1,000µga day
TimingWhenever you likeAny time of day.
FormCyanocobalamin or methylcobalamin
EU statusAuthorised · approved health claims (Regulation (EU) 432/2012)

250–1,000 µg a day (or 2,000–2,500 µg once a week).

01

What it is

Vegan and strict vegetarian diets have no reliable source, and it is practically the only supplement the scientific community considers essential on a vegan diet.

02

What it is used for

The quiz suggests it when your answers justify it. It usually appears with these goals:

03

What the evidence says

Strong

Consistent trials and reviews in people, or health claims authorised in the EU.

Authorised EU claim Vitamin B12 contributes to normal red blood cell formation and to the normal functioning of the nervous system. A vegan diet has no reliable natural sources: supplementing it is not optional.

YearWhat was studiedWhat was foundSource
2019Corrects deficiency in vegansRCT in vegans with marginal deficiency: it restored adequate B12 levels. A low, steady daily dose works better than weekly megadoses. Del Bo' et al.Clinical Nutrition
2023Why it is needed on a vegan dietReference review: everyone on a plant-based diet needs a reliable supplemented source of B12. Niklewicz et al.European Journal of Nutrition
04

What to look for on the label

  • A clear daily dose.
  • Cyanocobalamin is the most studied and most stable form.
05

Precautions

  • Very well tolerated.
  • If you have a diagnosed deficiency, follow your doctor’s advice.
06

Where to find it

Products whose label meets what this profile asks for: form, dose per serving and nothing that contradicts it. Three at most: quality of the active comes first and, among the best, we look for one option in each price range. We choose by composition, not by who pays. The shops are European or ship to Europe.

  1. NaturitasShips from SpainHigh end
    Solgar

    Vitamin B12 methylcobalamin 1000 µg

    1,000 µg of methylcobalamin per tablet

    For the reference dose1 tablet

    Meets the criteria.

    View at Naturitas (opens in a new tab)
  2. Life ExtensionShips from the NetherlandsMid range
    Life Extension

    Vitamin B12 methylcobalamin 500 µg

    500 µg per lozenge

    For the reference dose1 lozenge

    Meets the criteria.

    View at Life Extension (opens in a new tab)
  3. HSNShips from SpainBudget
    Essential Series

    Vitamin B12 cyanocobalamin 500 µg

    500 µg per tablet

    For the reference dose1 tablet

    Meets the criteria.

    View at HSN (opens in a new tab)

We link to the shop; we do not sell anything. Today we earn no commission on any link. If we ever do, the link will say so and the selection will not change: the label decides. Labels checked on 2 November 2026; check the one on the pack before you buy. All these shops deliver to the EU; some of their pages open in Spanish. How we are funded.

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Profile reviewed on 3 November 2026. Sources: EFSA, Regulation (EU) 432/2012 and published studies. Image: Chemical apparatus. Engraving by J. Pass, 1801. Wellcome Collection, public domain.

General information based on published scientific evidence and EU law. Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle, and are not intended to diagnose, treat or prevent any disease.

Do not exceed the daily dose stated on each product. If you take medication, have a medical condition or have any doubts, ask your doctor or pharmacist.