Phosphatidylserine
Phosphatidylserine is a phospholipid, one of the components of nerve cell membranes.
100–300 mg a day.
What it is
The body makes it, and the diet also provides it, especially fish and soy. Today’s supplements are made from soy or fish.
What it is used for
The quiz suggests it when your answers justify it. It usually appears with these goals:
What the evidence says
Trials in people that point the same way, but still few, small or funded by the manufacturer.
Trials in older adults show modest improvements in memory; in younger adults the evidence is limited. A few small studies on the stress response.
| Year | What was studied | What was found | Source |
|---|---|---|---|
| 2010 | Memory | 6-month trial with 78 people aged 50 to 69 with memory complaints: among those who started with lower scores, 100–300 mg a day improved verbal memory; the placebo group did not change. The authors are from a food company’s research centre. | Kato-Kataoka et al.Journal of Clinical Biochemistry and Nutrition |
| 2004 | Stress response | 3-week trial with 80 people: 400 mg of a phosphatidylserine and phosphatidic acid complex blunted the rise in cortisol and the feeling of stress during a social stress test. Higher doses had no effect. | Hellhammer et al.Stress |
What to look for on the label
- The forms authorised in the EU come from soy or fish: if you are allergic to one, choose the other.
Precautions
- If you are allergic to soy or fish, choose the other source.
- If you take anticoagulants, ask first.
Where to find it
Products whose label meets what this profile asks for: form, dose per serving and nothing that contradicts it. Three at most: quality of the active comes first and, among the best, we look for one option in each price range. We choose by composition, not by who pays. The shops are European or ship to Europe.
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iHerbShips from the US, VAT included€€€High endSolgar
Phosphatidylserine 200 mg
200 mg of soy phosphatidylserine per softgel
For the reference dose1 softgelView at iHerb (opens in a new tab)Meets the criteria.
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HSNShips from Spain€BudgetSwanson
Phosphatidylserine 100 mg (Sharp-PS®)
100 mg of soy phosphatidylserine per softgel
For the reference dose1–3 softgelsView at HSN (opens in a new tab)Meets the criteria.
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HSNShips from Spain€BudgetNow Foods
Phosphatidylserine 100 mg
100 mg of soy phosphatidylserine per capsule
For the reference dose1–3 capsulesView at HSN (opens in a new tab)Meets the criteria. Adds choline and inositol.
We link to the shop; we do not sell anything. Today we earn no commission on any link. If we ever do, the link will say so and the selection will not change: the label decides. Labels checked on 2 November 2026; check the one on the pack before you buy. All these shops deliver to the EU; some of their pages open in Spanish. How we are funded.
Nearby in the library
Is it for you?
The quiz decides from your answers, not from a profile.
Profile reviewed on 3 November 2026. Sources: EFSA, Regulation (EU) 432/2012 and published studies. Image: Design for a chemical laboratory. Etching by A.W. Warren, 1822. Wellcome Collection, public domain.
General information based on published scientific evidence and EU law. Food supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle, and are not intended to diagnose, treat or prevent any disease.
Do not exceed the daily dose stated on each product. If you take medication, have a medical condition or have any doubts, ask your doctor or pharmacist.